Ang Sulfobutylether-β-Cyclodextrin Pharmaceutical Excipient ay isang cyclodextrin derivativea at isang bagong uri ng mga excipients ng China Deli.
Sulfobutylether-β-Cyclodextrin Pharmaceutical Excipient
CAS: 182410-00-0
Appearance: White powder,sweet,insipid and innocuous
Shelf life: 36 Months
Grade: Injection grade
Application: Pharmaceuticals feild
Standard: USP, EP
Solubility:≥100(25℃,g/100ml)
Heavy metal:≤0.0025%
Reducing sugars: ≤0.05%
Product Description
Sulfobutylether-β-Cyclodextrin Pharmaceutical Excipient not only can increase drug solubility, improve the stability and safety of the drug, it can reduce the stimulation to the injection site of administration, the drug quickly reaches the blood concentration required, prolong the time of drug action.
Intranasal drug having rapid absorption, fast acting, high bioavailability, convenient administration, easy to be accepted by patients, and can avoid the liver first pass effect and other advantages, has become one of the hotspots in pharmaceutical research. However, due to low penetration of nasal drugs, many enzymes in the nasal cavity can cause degradation and nasal adhesion.
Sulfobutylether-β-Cyclodextrin Pharmaceutical Excipient is a sodium salt produced when Betadex is alkylated by 1,4-butanesulfonic acid lactone under alkaline conditions. It is an anion, highly water-soluble Betadex derivative. Sulfobutylether-β-Cyclodextrin Pharmaceutical Excipient can be well combined with the drug molecules to form non-covalent thereby enhancing the stability, water solubility, and safety of the drug, reducing its renal toxicity, easing drug hemolysis, controlling drug release rate, covering bad smell, etc.
